Found 10 matching trials
Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)
EARLY_PHASE1Endothelin-1 (ET-1) has been linked to a number of conditions including pul...
Location
Clinical Research Centre, Western General Hospital
A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses
PHASE1Sitaxsentan has a low drug-drug interaction potential and it did not have a...
Location
Pfizer Investigational Site
Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma
PHASE2Introduction. Despite adequate steroid therapy, a subpopulation of approxim...
Location
Clinical Investigation center 07, Hopital Bichat
Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery
PHASE2This is a multi-center, randomized study of sitaxsentan administered intrav...
Location
University of Pennsylvania,
Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)
N/AThe objectives of this study are to develop research methods and correspond...
Location
Multiple Locations
A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin
N/AThe Thelin Patient Safety Registry is a post-marketing program in the Europ...
Location
Pfizer Investigational Site
Pharmacogenomics in Pulmonary Arterial Hypertension
N/AOur goal is to determine clinically in Pulmonary Arterial Hypertension pati...
Location
Allegheny General Hospital
Sitaxsentan in Proteinuric Chronic Kidney Disease
PHASE2Patients with chronic kidney disease (CKD) have higher blood pressures than...
Location
Clinical Research Centre, Western General Hospital
Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension
PHASE3The purpose of this study is to evaluate the safety and efficacy of Thelin™...
Location
Encysive Pharmaceuticals
Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects
PHASE1The purpose of this study is to investigate safety, tolerability and pharma...
Location
Pfizer Investigational Site